LPR-1 localizes to both intracellular and apical extracellular compartments. Secreted protein. When driven by the
lpr-1 promoter, all fusions rescued
lpr-1 lethality and were detected within the duct and pore cells and other external epithelia beginning at the 1.5-fold stage. The fusions were also secreted apically between the embryo and the eggshell and appeared enriched in or near the duct and pore lumens at the 3-fold stage.