The mCherry-SAM- 10 signal was detected broadly throughout the animal with dense expression in the head ganglion,vulva and tail ganglion.
sam-10 expression was observed in PLM neurons. Furthermore, using GFP-RAB-3 as a nuclear-excluded marker in the PLM soma, was found that SAM- 10 was nuclearly localized in the PLM. The expression of was characterized using an mCherry-sam- 10 fusion transgene that fully rescues the
sam-10(
js94) phenotypes.