The gene is specifically expressed in neurons, and the transcript is exclusively localized also in neurons. unc-64 transcript is not detectable in hermaphrodite specific neurons. unc-64 gene is expressed in almost all neurons constituting the head ganglion.
We noted ciliary localization of the SRBC-64 G protein-coupled receptor to the ASK cilia but also detected significant accumulation at the periciliary membrane compartment (PCMC) in wild-type animals.
Embryonic expression of the cki-2 reporter starts at about the 64-cell stage in anteriorly located blastomeres. This expression pattern apparently continues throughout embryogenesis with a gradual increase in fluorescence intensity.
A 64-bp fragment, located between 366 and 303 bp upstream of the egl-17 ATG, was sufficient to activate reporter expression in vulD and vulC cells from mid-L4 through adulthood, termed the vulDC enhancer.