Northern (RNA) blot analysis of embryos at a variety of developmental stages revealed the presence of the Ce-cds-1
(which was called Ce-cds-1
/2) transcript. The expression of Ce-cds-1
/2 was first detectable at the L3 stage of larval development and became stronger as the worms reached adulthood. The expression of Ce-cds-1
/2 was detected in N2 wild-type adult animals but not in glp-4
mutants, indicating that Ce-cds-1
/2 expression in adults is dependent on the presence of a germline. The temporal expression pattern of Ce-cds-1
/2 is reminiscent of that of Dmnk, suggesting that Ce-CDS-1/2 may also be involved in meiosis and/or germline establishment.