ACBP-4::GFP is found to be specifically localized to granular structures in the intestine. These granules are likely to be fat storage granules, as ACBP- 4::GFP expression could not be observed upon RNAi (RNA interference) knockdown of sbp-1
, the C. elegans homologue of the mammalian lipogenic transcription factor SREBP-1c. Furthermore, under the light microscope, the ACBP-4::GFP-labelled granules have the smooth appearance of fat storage granules and not the more-obviously structured appearance of lysosomes. However, we cannot completely rule out the possibility that ACBP-4::GFP is also associated with lysosomes.