- spinal muscular atrophy [DOID:12377]
A motor neuron disease that is a degenerative neuromuscular disease characterized by lower motor neuron degeneration associated with progressive muscle weakness and atrophy.
- neuronitis [DOID:8117]
A central nervous system disease that is characterized by neuron inflammation.
- PEHO syndrome [DOID:0080539]
A brain disease that is characterized by extreme cerebellar atrophy due to almost total granule neuron loss.
- lateral sclerosis [DOID:230]
A motor neuron disease characterized by painless but progressive weakness and stiffness of the muscles of the legs.
- amyotrophic lateral sclerosis [DOID:332]
A motor neuron disease that is characterized by muscle spasticity, rapidly progressive weakness due to muscle atrophy, difficulty in speaking, swallowing, and breathing.
- amyotrophic lateral sclerosis type 26 [DOID:0081380]
An amyotrophic lateral sclerosis that is characterized by adult onset of upper and low motor neuron disease causing bulbar dysfunction and limb weakness and that has_material_basis_in heterozygous mutation in the TIA1 gene on chromosome 2p13.