- Cauda equina syndrome [DOID:11577]
A peripheral nervous system disease that involves an acute loss of function of the lumbar plexus, neurologic elements (nerve roots) of the spinal canal below the termination (conus) of the spinal cord.
- optic atrophy [DOID:5723]
An optic nerve disease that is characterized the death of the retinal ganglion cell axons that comprise the optic nerve.
- spinal muscular atrophy [DOID:12377]
A motor neuron disease that is a degenerative neuromuscular disease characterized by lower motor neuron degeneration associated with progressive muscle weakness and atrophy.
- neuronitis [DOID:8117]
A central nervous system disease that is characterized by neuron inflammation.
- ganglioneuroma [DOID:4817]
An autonomic nervous system benign neoplasm that is characterized by the presence of mature ganglion cells and a mature Schwannian stroma and arises from the sympathetic trunk in the mediastinum.
- optic atrophy 5 [DOID:0111438]
An optic atrophy characterized by degeneration of retinal ganglion cells resulting in slowly progressive visual loss with variable onset from the first to third decades that has_material_basis_in heterozygous of mutation in DNM1L on chromosome 12p11.21.