- Expression Data of Reactive Oxygen Species Signalling in C. elegans
We have shown that worms that possess mutations in two electron transport chain subunits live longer due to mtROS signalling. Wild type worms can also live longer by treatment with the pro-oxidant paraquat. Paraquat treatment is not additive to the mutations in the ETC subunits. We aimed to determine the underlying changes in gene expression that were common to both paraquat treatment and the two mutations. We also have shown genetically that the mtROS signal that leads to extended lifespan is dependent on CED-4. We generated double mutants that lack functional CED-4 with the two mutations in the ETC subunits. We have found that a large number of gene expression changes by mtROS signalling are reverted by loss of CED-4.
- Mean FPKM value of all japonica control samples
This is the mean value of the N=12 RNASeq FPKM expression values for this gene in all life-stage of this species of all samples in the SRA that are wildtype controls that do not appear to have undergone any experimental conditions or treatment that would affect gene expression.
- Median FPKM value of all japonica control samples
This is the median value of the N=12 RNASeq FPKM expression values for this gene in all life-stage of this species of all samples in the SRA that are wildtype controls that do not appear to have undergone any experimental conditions or treatment that would affect gene expression.
- Median FPKM value of all ovolvulus control samples
This is the median value of the N=12 RNASeq FPKM expression values for this gene in all life-stage of this species of all samples in the SRA that are wildtype controls that do not appear to have undergone any experimental conditions or treatment that would affect gene expression.