gene: set-16 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables histone H3K4 methyltransferase activity. Involved in programmed cell death and regulation of vulval development. Part of MLL3/4 complex. Expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; P5.p hermaphrodite; P8.p hermaphrodite; and linker cell. Human ortholog(s) of this gene implicated in several diseases, including Kabuki syndrome; Kleefstra syndrome 2; and carcinoma (multiple). Is an ortholog of human KMT2D (lysine methyltransferase 2D).