eat-4

Caenorhabditis elegans

Predicted to enable L-glutamate transmembrane transporter activity; glutamate:sodium symporter activity; and neurotransmitter transmembrane transporter activity. Involved in several processes, including glutamatergic synaptic transmission; positive regulation of backward locomotion; and regulation of male mating behavior. Predicted to be located in excitatory synapse and synaptic vesicle membrane. Expressed in intestine; neurons; and pharynx. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 25. Is an ortholog of human SLC17A7 (solute carrier family 17 member 7) and SLC17A8 (solute carrier family 17 member 8).

such-1

Caenorhabditis elegans

Predicted to be involved in anaphase-promoting complex-dependent catabolic process; positive regulation of mitotic metaphase/anaphase transition; and protein K11-linked ubiquitination. Predicted to be part of anaphase-promoting complex. Expressed in germ line; head neurons; sperm; and vulval precursor cell. Is an ortholog of human ANAPC5 (anaphase promoting complex subunit 5).

protein: SUCH-1

Caenorhabditis elegans

21ur-1

Caenorhabditis elegans

transcript: 3R5.1a.1 [Browse genome (BioProject PRJNA13758)]

Caenorhabditis elegans

protein: AAGR-1

Caenorhabditis elegans

protein: AAIM-1

Caenorhabditis elegans

aak-1

Caenorhabditis elegans

Predicted to enable protein serine/threonine kinase activity. Involved in negative regulation of cell population proliferation and pharyngeal pumping. Predicted to be part of nucleotide-activated protein kinase complex.

aakg-1

Caenorhabditis elegans

Predicted to enable AMP binding activity; protein kinase binding activity; and protein kinase regulator activity. Predicted to be involved in monoatomic ion transport. Predicted to be located in cytoplasm and nucleus. Predicted to be part of nucleotide-activated protein kinase complex. Human ortholog(s) of this gene implicated in Wolff-Parkinson-White syndrome; hypertrophic cardiomyopathy 6; and lethal congenital glycogen storage disease of heart. Is an ortholog of human PRKAG1 (protein kinase AMP-activated non-catalytic subunit gamma 1); PRKAG2 (protein kinase AMP-activated non-catalytic subunit gamma 2); and PRKAG3 (protein kinase AMP-activated non-catalytic subunit gamma 3).

aap-1

Caenorhabditis elegans

Enables protein kinase binding activity. Involved in dauer larval development; determination of adult lifespan; and insulin receptor signaling pathway. Part of phosphatidylinositol 3-kinase complex. Expressed in anchor cell; intestine; and neurons. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; SHORT syndrome; arthritis (multiple); and carcinoma (multiple). Is an ortholog of human PIK3R2 (phosphoinositide-3-kinase regulatory subunit 2).