gene: fax-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in several processes, including neuron differentiation; positive regulation of transcription by RNA polymerase II; and regulation of locomotion. Located in nucleus. Expressed in several structures, including CEP; hermaphrodite distal tip cell; interneuron; pharyngeal motor neurons; and rect_D. Human ortholog(s) of this gene implicated in enhanced S-cone syndrome and retinitis pigmentosa 37. Is an ortholog of human NR2E3 (nuclear receptor subfamily 2 group E member 3).