Enables acetylcholine-gated monoatomic cation-selective channel activity. Involved in several processes, including feeding behavior; regulation of eating behavior; and regulation of gene expression. Located in neuromuscular junction and plasma membrane. Part of acetylcholine-gated channel complex. Expressed in
pm4 and
pm5. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Lewy body dementia; carcinoma (multiple); and inflammatory bowel disease (multiple). Is an ortholog of human CHRFAM7A (CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion) and CHRNA7 (cholinergic receptor nicotinic alpha 7 subunit).