gene: anc-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable actin binding activity and kinesin binding activity. Involved in cytoskeleton organization; nucleus organization; and pronuclear migration. Located in nuclear envelope and perinuclear region of cytoplasm. Expressed in several structures, including body wall musculature; intestinal cell; and vulval muscle. Used to study Emery-Dreifuss muscular dystrophy. Human ortholog(s) of this gene implicated in arthrogryposis multiplex congenita-3; autosomal dominant Emery-Dreifuss muscular dystrophy 4; autosomal dominant Emery-Dreifuss muscular dystrophy 5; autosomal recessive spinocerebellar ataxia 8; and bipolar disorder. Is an ortholog of human SYNE1 (spectrin repeat containing nuclear envelope protein 1).
sequence feature: WBsf716915
Caenorhabditis elegans This is a predicted enhancer region. These are intergenic TF-binding sites >500 bp from a gene start which overlap a TSS cluster, excluding regions that appear to be unannotated promoters based on having a signature of high H3K4me3/low H3K4me1. Nearest downstream gene=ZK973.6. Surounding gene organisation=tandem