gene: gap-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Predicted to enable GTPase activator activity. Involved in learning or memory and negative regulation of Ras protein signal transduction. Predicted to be located in cytoplasm. Expressed in several structures, including head muscle; head neurons; non-striated muscle; tail; and vulva. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 5; gastrointestinal system cancer (multiple); and lung non-small cell carcinoma. Is an ortholog of human DAB2IP (DAB2 interacting protein); RASAL2 (RAS protein activator like 2); and SYNGAP1 (synaptic Ras GTPase activating protein 1).