gene: mec-7 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Involved in cytoplasmic microtubule organization; positive regulation of multicellular organismal process; and response to mechanical stimulus. Located in neuron projection and neuronal cell body. Expressed in BDU and mechanosensory neurons. Used to study hypokalemic periodic paralysis. Human ortholog(s) of this gene implicated in Leber congenital amaurosis with early-onset deafness; brain disease (multiple); and congenital symmetric circumferential skin creases 1. Is an ortholog of human TUBB (tubulin beta class I); TUBB4A (tubulin beta 4A class IVa); and TUBB4B (tubulin beta 4B class IVb).