Predicted to enable GTP binding activity; GTPase activity; and protein kinase binding activity. Involved in establishment or maintenance of cell polarity and vulval development. Predicted to be located in plasma membrane. Expressed in several structures, including P3.pa; P3.pp; P4.pa; P4.pp; and P8.pa. Is an ortholog of human RHOU (ras homolog family member U).
Enriched in Z1.p; Z4.a; gon_male_dtc anterior; and gon_male_dtc posterior based on RNA-seq studies. Is affected by daf-2 based on microarray studies. Is affected by triclosan based on microarray studies.
Predicted to enable metal ion binding activity. Expressed in several structures, including Z4.ap; dorsal uterine precursor; head muscle; head neurons; and ventral uterine precursor. Is an ortholog of human ZNF501 (zinc finger protein 501).
Enriched in NSM; Z1.p; Z4.a; gon_male_dtc anterior; and gon_male_dtc posterior based on tiling array and RNA-seq studies. Is affected by rsr-2 and clk-1 based on tiling array and microarray studies.
Predicted to enable dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity. Predicted to be located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Id. Is an ortholog of human ALG3 (ALG3 alpha-1,3- mannosyltransferase).