gene: hsf-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables several functions, including calmodulin binding activity; identical protein binding activity; and promoter-specific chromatin binding activity. Involved in several processes, including ascaroside biosynthetic process; defense response to other organism; and positive regulation of metabolic process. Located in cytoplasm; nuclear body; and nuclear stress granule. Part of chromatin. Expressed in several structures, including germ cell; hypodermis; intestine; neurons; and somatic cell. Human ortholog(s) of this gene implicated in Huntington's disease and cataract 5 multiple types. Is an ortholog of human HSF1 (heat shock transcription factor 1) and HSF2 (heat shock transcription factor 2).
sequence feature: WBsf717585
Caenorhabditis elegans This is a predicted enhancer region. These are intergenic TF-binding sites >500 bp from a gene start which overlap a TSS cluster, excluding regions that appear to be unannotated promoters based on having a signature of high H3K4me3/low H3K4me1. Nearest downstream gene=Y53C10A.12. Surounding gene organisation=tandem