Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding activity. Involved in developmental process involved in reproduction; negative regulation of transcription by RNA polymerase II; and positive regulation of neuron apoptotic process. Located in cytoplasm and nucleus. Expressed in several structures, including AWA; germ line; gonad; intestine; and somatic cell. Human ortholog(s) of this gene implicated in several diseases, including Culler-Jones syndrome; gastrointestinal system cancer (multiple); and synostosis (multiple). Is an ortholog of human GLI1 (GLI family zinc finger 1); GLI2 (GLI family zinc finger 2); and GLI3 (GLI family zinc finger 3).
This is a predicted enhancer region. These are intergenic TF-binding sites >500 bp from a gene start which overlap a TSS cluster, excluding regions that appear to be unannotated promoters based on having a signature of high H3K4me3/low H3K4me1. Nearest downstream gene=Y47D3A.6. Surounding gene organisation=tandem
This is a predicted enhancer region. These are intergenic TF-binding sites >500 bp from a gene start which overlap a TSS cluster, excluding regions that appear to be unannotated promoters based on having a signature of high H3K4me3/low H3K4me1. Nearest downstream gene=Y47D3A.16. Surounding gene organisation=tandem