gene: nkcc-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable sodium:potassium:chloride symporter activity. Predicted to be involved in cell volume homeostasis; inorganic ion homeostasis; and monoatomic ion transmembrane transport. Predicted to be located in membrane. Expressed in body wall musculature; intestine; neurons; oocyte; and vulval muscle. Human ortholog(s) of this gene implicated in several diseases, including autosomal dominant nonsyndromic deafness 78; middle cerebral artery infarction; and renal tubular transport disease (multiple). Is an ortholog of human SLC12A1 (solute carrier family 12 member 1) and SLC12A2 (solute carrier family 12 member 2).
sequence feature: WBsf717203
Caenorhabditis elegans This is a predicted enhancer region. These are intergenic TF-binding sites >500 bp from a gene start which overlap a TSS cluster, excluding regions that appear to be unannotated promoters based on having a signature of high H3K4me3/low H3K4me1. Nearest downstream gene=Y37A1C.1. Surounding gene organisation=tandem