Enables protein-tyrosine sulfotransferase activity. Involved in several processes, including collagen metabolic process; cuticle development involved in collagen and cuticulin-based cuticle molting cycle; and regulation of nematode larval development. Located in trans-Golgi network. Expressed in AIYL; AIYR; head neurons; and hypodermis. Human ortholog(s) of this gene implicated in colorectal adenocarcinoma. Is an ortholog of human TPST1 (tyrosylprotein sulfotransferase 1) and TPST2 (tyrosylprotein sulfotransferase 2).