gene: dpy-23 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable clathrin adaptor activity. Involved in several processes, including necroptotic process; positive regulation of Wnt protein secretion; and protein localization to non-motile cilium. Located in periciliary membrane compartment and synaptic vesicle. Expressed in anal depressor muscle; germ line; neurons; rectal epithelial cell; and spermatheca. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder. Is an ortholog of human AP2M1 (adaptor related protein complex 2 subunit mu 1).