gene: elt-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including epidermal cell fate specification; regulation of transcription by RNA polymerase II; and spermatid development. Located in nucleus. Expressed in several structures, including V1L.a; V1R.a; V2L.a; seam cell; and vulval muscle. Human ortholog(s) of this gene implicated in several diseases, including X-linked recessive disease (multiple); bone marrow cancer (multiple); and carcinoma (multiple). Is an ortholog of human GATA1 (GATA binding protein 1); GATA2 (GATA binding protein 2); and GATA3 (GATA binding protein 3).
sequence feature: WBsf718160
Caenorhabditis elegans This is a predicted enhancer region. These are intergenic TF-binding sites >500 bp from a gene start which overlap a TSS cluster, excluding regions that appear to be unannotated promoters based on having a signature of high H3K4me3/low H3K4me1. Nearest downstream gene=W09C2.1. Surounding gene organisation=divergent