gene: unc-55 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Involved in cell fate specification and negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in motor neurons; somatic nervous system; and spicule muscle. Human ortholog(s) of this gene implicated in 46,XX sex reversal 5 and Bosch-Boonstra-Schaaf optic atrophy syndrome. Is an ortholog of human NR2F1 (nuclear receptor subfamily 2 group F member 1) and NR2F2 (nuclear receptor subfamily 2 group F member 2).