Enriched in neurons; retrovesicular ganglion; and somatic gonad precursor based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including
daf-16;
daf-2; and
clk-1 based on microarray; RNA-seq; and proteomic studies. Is affected by ten chemicals including rotenone; allantoin; and Sirolimus based on RNA-seq and microarray studies. Used to study mucopolysaccharidosis. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2V and mucopolysaccharidosis type IIIB. Is predicted to encode a protein with the following domains: Glycoside hydrolase superfamily; Alpha-N-acetylglucosaminidase; Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain; Alpha-N-acetylglucosaminidase, tim-barrel domain; Alpha-N-acetylglucosaminidase, C-terminal; and Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain. Is an ortholog of human NAGLU (N-acetyl-alpha-glucosaminidase).