gene: pen-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Involved in several processes, including Notch signaling pathway; cell differentiation; and pharynx development. Located in membrane. Expressed in intestine; muscle cell; neurons; and vulva. Human ortholog(s) of this gene implicated in hidradenitis suppurativa. Is an ortholog of human PSENEN (presenilin enhancer, gamma-secretase subunit).