Is predicted to encode a protein with the following domains: Abnormal spindle-like microcephaly-associated protein; Armadillo-type fold; Immunoglobulin-like fold; Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin; Abnormal spindle-like microcephaly-associated protein, ASH domain; Calponin homology domain; IQ motif, EF-hand binding site; CH domain superfamily; Calponin homology (CH) domain; and IQ calmodulin-binding motif. Is an ortholog of C. elegans
aspm-1 and
ehbp-1. In C. elegans,
aspm-1 is involved in establishment of meiotic spindle orientation; meiotic spindle organization; and regulation of protein localization.