- gene: him-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables DNA binding activity. Involved in chromosome segregation; embryo development; and response to radiation. Located in nucleus. Part of chromatin and cohesin complex. Expressed in linker cell. Human ortholog(s) of this gene implicated in Cornelia de Lange syndrome 2; congestive heart failure; and developmental and epileptic encephalopathy 85. Is an ortholog of human SMC1B (structural maintenance of chromosomes 1B).
- gene: smc-4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable ATP binding activity and ATP hydrolysis activity. Involved in mitotic sister chromatid segregation and positive regulation of nematode male tail tip morphogenesis. Located in chromosome, centromeric region and condensed chromosome. Expressed in head; linker cell; and tail. Is an ortholog of human SMC4 (structural maintenance of chromosomes 4).
- gene: tim-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable DNA binding activity. Involved in embryo development; regulation of sister chromatid cohesion; and sister chromatid cohesion. Located in nucleus. Human ortholog(s) of this gene implicated in advanced sleep phase syndrome. Is an ortholog of human TIMELESS (timeless circadian regulator).
- gene: capg-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Involved in mitotic sister chromatid segregation. Predicted to be located in nucleus. Predicted to be part of condensin complex. Is an ortholog of human NCAPG2 (non-SMC condensin II complex subunit G2).
- gene: kle-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable chromatin binding activity. Involved in mitotic sister chromatid segregation. Predicted to be located in nucleus. Predicted to be part of condensin complex. Is an ortholog of human NCAPH2 (non-SMC condensin II complex subunit H2).
- strain: GE4345
Caenorhabditis elegans - gene: rec-8 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable chromatin binding activity and damaged DNA binding activity. Involved in double-strand break repair and organelle organization. Located in nuclear lumen and spindle. Part of chromatin. Expressed in Z2; Z3; embryonic cell; and gonad.
- strain: KIR1
Caenorhabditis elegans - gene: scc-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable DNA binding activity and chromatin binding activity. Involved in organelle organization and regulation of DNA damage checkpoint. Located in condensed chromosome. Part of chromatin and cohesin complex. Expressed in gonad. Human ortholog(s) of this gene implicated in several diseases, including intellectual disability (multiple); primary ovarian insufficiency 8; and spermatogenic failure 61. Is an ortholog of human STAG1 (STAG1 cohesin complex component) and STAG2 (STAG2 cohesin complex component).