gene: sms-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable ceramide cholinephosphotransferase activity and sphingomyelin synthase activity. Predicted to be involved in ceramide biosynthetic process and sphingomyelin biosynthetic process. Predicted to be located in Golgi membrane. Expressed in head muscle; pharyngeal cell; rectal muscle; spermatheca; and vulval muscle. Human ortholog(s) of this gene implicated in calvarial doughnut lesions with bone fragility. Is an ortholog of human SGMS2 (sphingomyelin synthase 2).