- strain: XE1311
Caenorhabditis elegans - gene: tph-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable tryptophan 5-monooxygenase activity. Involved in several processes, including determination of adult lifespan; locomotory exploration behavior; and positive regulation of transforming growth factor beta receptor signaling pathway. Located in cytosol and neuron projection. Expressed in CP neuron; nerve ring; and pharynx. Used to study alcohol use disorder and cocaine abuse. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; alcohol use disorder; attention deficit hyperactivity disorder; and autistic disorder. Is an ortholog of human TPH1 (tryptophan hydroxylase 1) and TPH2 (tryptophan hydroxylase 2).
- strain: HCC21
Caenorhabditis elegans - gene: rpt-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable proteasome-activating activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nucleus. Predicted to be part of proteasome regulatory particle, base subcomplex. Is an ortholog of human PSMC4 (proteasome 26S subunit, ATPase 4).
- gene: rpt-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable proteasome-activating activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nucleus. Predicted to be part of proteasome regulatory particle, base subcomplex. Is an ortholog of human PSMC5 (proteasome 26S subunit, ATPase 5).
- gene: rpt-5 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable proteasome-activating activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nucleus. Predicted to be part of proteasome regulatory particle, base subcomplex. Expressed in head and tail. Used to study obesity. Is an ortholog of human PSMC3 (proteasome 26S subunit, ATPase 3).
- strain: HCC31
Caenorhabditis elegans - strain: HCC27
Caenorhabditis elegans