gene: unc-8 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable ligand-gated sodium channel activity. Involved in locomotion. Located in neuronal cell body. Expressed in neurons. Human ortholog(s) of this gene implicated in bronchiectasis (multiple) and renal tubular transport disease (multiple). Is an ortholog of human SCNN1B (sodium channel epithelial 1 subunit beta); SCNN1D (sodium channel epithelial 1 subunit delta); and SCNN1G (sodium channel epithelial 1 subunit gamma).