gene: ppm-1.A [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable protein serine/threonine phosphatase activity. Predicted to be involved in negative regulation of stress-activated MAPK cascade. Predicted to be located in cytosol and nucleus. Is an ortholog of human PPM1A (protein phosphatase, Mg2+/Mn2+ dependent 1A) and PPM1B (protein phosphatase, Mg2+/Mn2+ dependent 1B).
gene: ppm-1.D [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable mitogen-activated protein kinase binding activity and protein serine/threonine phosphatase activity. Predicted to be involved in negative regulation of gene expression, epigenetic. Predicted to be located in cytosol and nucleus. Expressed in distal tip cell and germline blastomere. Human ortholog(s) of this gene implicated in breast cancer and pre-malignant neoplasm. Is an ortholog of human PPM1D (protein phosphatase, Mg2+/Mn2+ dependent 1D).