- gene: tsp-20 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be located in membrane. Human ortholog(s) of this gene implicated in epidermolysis bullosa simplex. Is an ortholog of several human genes including CD151 (CD151 molecule (Raph blood group)); CD37 (CD37 molecule); and TSPAN16 (tetraspanin 16).
- gene: rig-4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be involved in cell adhesion. Predicted to be located in membrane. Expressed in several structures, including DA neuron; excretory cell; somatic neurons; spermathecal-uterine junction; and vulva. Is an ortholog of human SDK1 (sidekick cell adhesion molecule 1) and SDK2 (sidekick cell adhesion molecule 2).
- gene: rpn-6.2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable structural molecule activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to be part of proteasome regulatory particle, lid subcomplex.
- gene: zig-10 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be involved in synapse organization. Predicted to be located in neuron projection membrane. Expressed in cholinergic neurons; head neurons; hypodermis; and seam cell. Human ortholog(s) of this gene implicated in several diseases, including basal ganglia calcification; hypertension; and systemic scleroderma. Is an ortholog of human F11R (F11 receptor); JAM2 (junctional adhesion molecule 2); and JAM3 (junctional adhesion molecule 3).
- strain: NM1657
Caenorhabditis elegans - gene: ncam-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable cell-cell adhesion mediator activity. Predicted to be involved in axon guidance; dendrite self-avoidance; and homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to be located in axon and plasma membrane. Expressed in several structures, including GLR; germ line; neurons; somatic nervous system; and spermatheca. Human ortholog(s) of this gene implicated in several diseases, including brain glioblastoma multiforme; carcinoma (multiple); and insulinoma. Is an ortholog of human NCAM1 (neural cell adhesion molecule 1) and NCAM2 (neural cell adhesion molecule 2).