- clone: M5
Caenorhabditis elegans - gene: xrn-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables 5'-3' RNA exonuclease activity. Involved in several processes, including miRNA catabolic process; negative regulation of miRNA-mediated gene silencing; and regulation of vulval development. Located in nucleus. Expressed in M5 neuron; PVT; intestine; and pharyngeal epithelial cell. Human ortholog(s) of this gene implicated in adenoid cystic carcinoma; leiomyosarcoma; and lung cancer. Is an ortholog of human XRN2 (5'-3' exoribonuclease 2).
- gene: flp-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables neuropeptide receptor binding activity. Involved in several processes, including mechanosensory behavior; regulation of egg-laying behavior; and response to serotonin. Predicted to be located in extracellular region. Expressed in RIG; nerve ring; and neurons.
- gene: ser-7 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable G protein-coupled serotonin receptor activity and neurotransmitter receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger and chemical synaptic transmission. Located in membrane. Expressed in pharyngeal neurons and vulval muscle. Human ortholog(s) of this gene implicated in alcohol use disorder. Is an ortholog of human HTR7 (5-hydroxytryptamine receptor 7).