gene: dcr-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables deoxyribonuclease I activity and ribonuclease III activity. Involved in several processes, including nucleic acid metabolic process; olfactory learning; and positive regulation of primary miRNA processing. Acts upstream of or within defense response to Gram-positive bacterium. Located in cytosol and nucleus. Expressed in germ line; intestine; neurons; and somatic cell. Human ortholog(s) of this gene implicated in several diseases, including DICER1 syndrome; gastrointestinal system cancer (multiple); and multinodular goiter. Is an ortholog of human DICER1 (dicer 1, ribonuclease III).