gene: jac-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables cadherin binding activity. Involved in embryonic body morphogenesis; regulation of actin cytoskeleton organization; and regulation of protein localization. Located in adherens junction. Part of catenin complex. Expressed in head. Human ortholog(s) of this gene implicated in several diseases, including DiGeorge syndrome; blepharocheilodontic syndrome 2; and oral squamous cell carcinoma. Is an ortholog of human ARVCF (ARVCF delta catenin family member).