Predicted to enable inositol 1,4,5 trisphosphate binding activity and inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity. Predicted to be involved in calcium ion transmembrane transport. Predicted to be located in endoplasmic reticulum and membrane. Is an ortholog of C. elegans chrIV_pilon.g10889
. In C. elegans, itr-1
is involved in several processes, including hermaphrodite genitalia morphogenesis; multicellular organismal reproductive process; and system process.