gene: itr-1 [Browse genome (BioProject PRJNA13758)] [Legacy GBrowse] [Search on AGR]
Enables myosin binding activity. Involved in several processes, including hermaphrodite genitalia morphogenesis; multicellular organismal reproductive process; and system process. Located in endoplasmic reticulum and membrane. Expressed in several structures, including egg-laying apparatus; ganglia; gonad; non-striated muscle; and tail hypodermis. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Gillespie syndrome; and isolated anhidrosis with normal sweat glands. Is an ortholog of human ITPR1 (inositol 1,4,5-trisphosphate receptor type 1).