Is predicted to enable ATP binding activity and mismatched DNA binding activity. Is involved in chiasma assembly; embryo development; and resolution of meiotic recombination intermediates. Located in nucleus. Is expressed in embryonic cell and gonad. Is an ortholog of human MSH4 (mutS homolog 4).
Is predicted to enable structural molecule activity. Is involved in chromosome segregation and organelle organization. Located in kinetochore. Part of Ndc80 complex. Human ortholog(s) of this gene are implicated in several diseases, including gastrointestinal system cancer (multiple); lung cancer (multiple); and oral cavity carcinoma in situ. Is an ortholog of human NUF2 (NUF2 component of NDC80 kinetochore complex).
Enables enzyme binding activity and identical protein binding activity. Is involved in DNA metabolic process; chromosome segregation; and embryo development. Located in nucleus. Part of Slx1-Slx4 complex. Is expressed in germ line. Human ortholog(s) of this gene are implicated in Fanconi anemia complementation group P. Is an ortholog of human SLX4 (SLX4 structure-specific endonuclease subunit).
Enables DNA binding activity. Is involved in regulation of centriole-centriole cohesion and synaptonemal complex assembly. Located in lateral element. Is expressed in oocyte and spermatocyte. Is an ortholog of human HORMAD1 (HORMA domain containing 1) and HORMAD2 (HORMA domain containing 2).