gene: tax-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Contributes to intracellular cGMP-activated cation channel activity. Involved in several processes, including G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger; negative regulation of cGMP-mediated signaling; and positive regulation of macromolecule metabolic process. Part of cation channel complex. Expressed in ciliated neurons. Human ortholog(s) of this gene implicated in achromatopsia 3 and retinitis pigmentosa 45. Is an ortholog of human CNGB1 (cyclic nucleotide gated channel subunit beta 1) and CNGB3 (cyclic nucleotide gated channel subunit beta 3).