gene: gon-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables metallopeptidase activity. Involved in several processes, including endoplasmic reticulum to Golgi vesicle-mediated transport; muscle organ morphogenesis; and negative regulation of presynapse assembly. Predicted to be located in extracellular matrix. Expressed in amphid neurons; excretory cell; gonad; motor neurons; and muscle cell. Used to study obesity and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in rheumatoid arthritis. Is an ortholog of human ADAMTS20 (ADAM metallopeptidase with thrombospondin type 1 motif 20) and ADAMTS9 (ADAM metallopeptidase with thrombospondin type 1 motif 9).
sequence feature: WBsf716788
Caenorhabditis elegans This is a predicted enhancer region. These are intergenic TF-binding sites >500 bp from a gene start which overlap a TSS cluster, excluding regions that appear to be unannotated promoters based on having a signature of high H3K4me3/low H3K4me1. Nearest downstream gene=F25H8.3. Surounding gene organisation=divergent
sequence feature: WBsf718166
Caenorhabditis elegans This is a predicted enhancer region. These are intergenic TF-binding sites >500 bp from a gene start which overlap a TSS cluster, excluding regions that appear to be unannotated promoters based on having a signature of high H3K4me3/low H3K4me1. Nearest downstream gene=F25H8.3. Surounding gene organisation=divergent