gene: hpk-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable protein serine/threonine kinase activity and protein tyrosine kinase activity. Involved in several processes, including autophagosome assembly; determination of adult lifespan; and response to heat. Located in nucleus. Expressed in several structures, including gonad and neurons. Used to study Parkinson's disease. Is an ortholog of human HIPK1 (homeodomain interacting protein kinase 1); HIPK2 (homeodomain interacting protein kinase 2); and HIPK3 (homeodomain interacting protein kinase 3).