gene: lin-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables insulin-like growth factor receptor binding activity. Involved in several processes, including egg-laying behavior; positive regulation of vulval development; and protein localization to membrane. Located in cell junction. Expressed in several structures, including CAN; HSN; isthmus; somatic nervous system; and vulval precursor cell. Used to study autism spectrum disorder. Human ortholog(s) of this gene implicated in FG syndrome and syndromic X-linked intellectual disability Najm type. Is an ortholog of human CASK (calcium/calmodulin dependent serine protein kinase).