gene: dop-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables dopamine neurotransmitter receptor activity, coupled via Gs; epinephrine binding activity; and norepinephrine binding activity. Involved in several processes, including adenylate cyclase-activating dopamine receptor signaling pathway; habituation; and mechanosensory behavior. Predicted to be located in dendrite. Expressed in several structures, including accessory cell; excretory gland cell; head muscle; mechanosensory neurons; and neurons. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; attention deficit hyperactivity disorder; blepharospasm; and kidney failure. Is an ortholog of human DRD1 (dopamine receptor D1).
sequence feature: WBsf718562
Caenorhabditis elegans This is a predicted enhancer region. These are intergenic TF-binding sites >500 bp from a gene start which overlap a TSS cluster, excluding regions that appear to be unannotated promoters based on having a signature of high H3K4me3/low H3K4me1. Nearest downstream gene=F15A8.5. Surounding gene organisation=tandem