gene: nhr-25 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables armadillo repeat domain binding activity. Involved in molting cycle and positive regulation of nematode male tail tip morphogenesis. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in several structures, including excretory system; gonad; hypodermal cell; tail; and vulval precursor cell. Human ortholog(s) of this gene implicated in several diseases, including Zellweger syndrome; gonadal dysgenesis (multiple); and primary ovarian insufficiency 7. Is an ortholog of human NR5A2 (nuclear receptor subfamily 5 group A member 2).
sequence feature: WBsf716883
Caenorhabditis elegans This is a predicted enhancer region. These are intergenic TF-binding sites >500 bp from a gene start which overlap a TSS cluster, excluding regions that appear to be unannotated promoters based on having a signature of high H3K4me3/low H3K4me1. Nearest downstream gene=F11C1.6. Surounding gene organisation=tandem
sequence feature: WBsf718739
Caenorhabditis elegans This is a predicted enhancer region. These are intergenic TF-binding sites >500 bp from a gene start which overlap a TSS cluster, excluding regions that appear to be unannotated promoters based on having a signature of high H3K4me3/low H3K4me1. Nearest downstream gene=F11C1.6. Surounding gene organisation=tandem