gene: pkc-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables protein domain specific binding activity and protein serine/threonine kinase activity. Involved in several processes, including antifungal innate immune response; gonad development; and response to wounding. Located in apical plasma membrane; cortical actin cytoskeleton; and cytosol. Expressed in several structures, including Psub4; enteric muscle; hypodermis; pharyngeal-intestinal valve; and vulva. Human ortholog(s) of this gene implicated in invasive ductal carcinoma and ovarian carcinoma. Is an ortholog of human PRKCI (protein kinase C iota) and PRKCZ (protein kinase C zeta).