- expression cluster: WBPaper00048706:productive-tract_enriched
Protein quantitation was determined by normalized spectral abundance.Proteins with NSAF enrichment values of 2 or greater were were considered enriched within that fraction.
Proteins that are enriched in productive tract of adult female Brugia malayi.
- expression cluster: WBPaper00048706:digestive-tract_enriched
Protein quantitation was determined by normalized spectral abundance.Proteins with NSAF enrichment values of 2 or greater were were considered enriched within that fraction.
Proteins that are enriched in digestive tract of adult female Brugia malayi.
- expression cluster: WBPaper00048706:body-wall-tract_enriched
Protein quantitation was determined by normalized spectral abundance.Proteins with NSAF enrichment values of 2 or greater were were considered enriched within that fraction.
Proteins that are enriched in body wall tract of adult female Brugia malayi.
- expression cluster: WBPaper00051007:downregulated_M42_vs_M30
EdgeR(v3.16.5), FDR < 0.05.
Transcripts that showed significantly decreased expression in male B. malayi 42 days after infecting gerbils, comparing to 30 days after infecting gerbils.
- expression cluster: WBPaper00051007:downregulated_F120_vs_F42
EdgeR(v3.16.5), FDR < 0.05.
Transcripts that showed significantly decreased expression in female B. malayi 120 days after infecting gerbils, comparing to 42 days after infecting gerbils.
- expression cluster: WBPaper00051007:downregulated_M42_vs_F42
EdgeR(v3.16.5), FDR < 0.05.
Transcripts that showed significantly decreased expression in male B. malayi 42 days after infecting gerbils, comparing to female B. malayi 42 days after infecting gerbils.
- expression cluster: WBPaper00051007:downregulated_F30_vs_L4
EdgeR(v3.16.5), FDR < 0.05.
Transcripts that showed significantly decreased expression in female B. malayi 30 days after infecting gerbils, comparing to L4 female B. malayi animals.
- expression cluster: WBPaper00051007:downregulated_F42_vs_F30
EdgeR(v3.16.5), FDR < 0.05.
Transcripts that showed significantly decreased expression in female B. malayi 42 days after infecting gerbils, comparing to 30 days after infecting gerbils.
- expression cluster: WBPaper00049974:ivermectin_100nM_24h_upregulated
Differential gene expression analysis between time points and drug concentrations was realized in edgeR (version 3.10.5) through the web interface provided by NetworkAnalyst. Significance was set as an experiment-wide false discovery rate (FDR) <0.20 (after the Benjamini-Hochberg method).
Transcripts that showed significantly increased expression after 24 hours of 100nM ivermectin exposure.
- expression cluster: WBPaper00049974:ivermectin_1uM_5-day_upregulated
Differential gene expression analysis between time points and drug concentrations was realized in edgeR (version 3.10.5) through the web interface provided by NetworkAnalyst. Significance was set as an experiment-wide false discovery rate (FDR) <0.20 (after the Benjamini-Hochberg method).
Transcripts that showed significantly increased expression after 5 days of 1uM ivermectin exposure.