Is predicted to encode a protein with the following domains: HUWE1/Rev1, ubiquitin binding region; Domain of Unknown Function (DUF913); Ubiquitin binding region; UBA-like superfamily; Domain of Unknown Function (DUF908); E3 ubiquitin ligase, domain of unknown function DUF908; Ubiquitin-associated domain; E3 ubiquitin ligase, domain of unknown function DUF913; and UBA/TS-N domain. Is an ortholog of C. elegans
eel-1. In C. elegans,
eel-1 is involved in several processes, including asymmetric protein localization involved in cell fate determination; hemidesmosome assembly; and signal transduction in response to DNA damage.