gene: egl-8 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable phosphatidylinositol phospholipase C activity. Involved in several processes, including dopamine receptor signaling pathway; positive regulation of acetylcholine secretion, neurotransmission; and taxis. Located in plasma membrane. Expressed in intestine; nervous system; non-striated muscle; and vas deferens. Used to study nicotine dependence. Is an ortholog of human PLCB4 (phospholipase C beta 4).