gene: din-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination and ubiquitin-dependent protein catabolic process. Located in nucleus. Expressed in several structures, including body wall musculature; hermaphrodite distal tip cell; intestine; pharynx; and vulval precursor cell. Human ortholog(s) of this gene implicated in esophagus squamous cell carcinoma and nasopharynx carcinoma. Is an ortholog of human SPEN (spen family transcriptional repressor).