gene: eat-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable GTPase activity and microtubule binding activity. Involved in several processes, including mitochondrial fusion; nematode larval development; and response to superoxide. Located in mitochondrion. Expressed in intestinal cell; muscle cell; and neurons. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Behr syndrome; dominant optic atrophy plus syndrome; and mitochondrial DNA depletion syndrome 14. Is an ortholog of human OPA1 (OPA1 mitochondrial dynamin like GTPase).